|
Symbol Name ID |
Fcgr4
Fc receptor, IgG, low affinity IV MGI:2179523 |
| * | Aspects of the system are reported to show a normal phenotype. |
| Darker colors indicate more annotations |
| Human Phenotypes | Reduced natural killer cell activity |
Monoclonal immunoglobulin M proteinemia |
Polyclonal elevation of IgM |
Leukopenia |
Reduced natural killer cell count |
Impaired lymphocyte transformation with phytohemagglutinin |
Abnormality of neutrophils |
Hemophagocytosis |
Leukemia |
Recurrent sinusitis |
Stomatitis |
Recurrent pharyngitis |
Recurrent viral upper respiratory tract infections |
Pericarditis |
Lymphadenopathy |
Mediastinal lymphadenopathy |
Splenomegaly |
Hepatosplenomegaly |
Gastrointestinal inflammation |
Recurrent gastroenteritis |
Acute hepatitis |
Chronic hepatitis |
Recurrent otitis media |
Iridocyclitis |
Inflammatory abnormality of the eye |
Epididymitis |
Lupus nephritis |
Nephritis |
Abnormality of the immune system |
Fasciitis |
Inflammatory abnormality of the skin |
Erythema nodosum |
Discoid lupus rash |
Maculopapular exanthema |
Malar rash |
Myositis |
Pneumonia |
Serositis |
Decreased circulating complement C3 concentration |
Decreased circulating complement C4 concentration |
Cryoglobulinemia |
Anti-citrullinated protein antibody positivity |
Antineutrophil antibody positivity |
Perinuclear antineutrophil antibody positivity |
Antinuclear antibody positivity |
Anti-dsDNA antibody positivity |
Anti-La/SS-B antibody positivity |
Anti-Sm antibody positivity |
Anti-U1 ribonucleoprotein antibody positivity |
Antiphospholipid antibody positivity |
Platelet antibody positive |
Rheumatoid factor positive |
Systemic lupus erythematosus |
Immunodeficiency |
Asthma |
BCGitis |
Recurrent infections |
Recurrent respiratory infections |
Severe varicella zoster infection |
Meningitis |
Recurrent oral herpes |
| Disease(s) Associated with FCGR3A | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| asthma | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| autoimmune thrombocytopenic purpura | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Behcet's disease | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| graft-versus-host disease | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| IgA glomerulonephritis | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| immunodeficiency 20 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| lymphoplasmacytic lymphoma | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| myositis | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| rheumatoid arthritis | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| systemic lupus erythematosus | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| temporal arteritis |
| Mouse Phenotypes | immune system phenotype |
decreased osteoclast cell number |
decreased susceptibility to induced arthritis |
arthritis |
|
| Availability | Mouse Genotype | ||||
| Fcgr4tm1.1Rav/Fcgr4tm1.1Rav | * | ||||
| Fcgr4tm1Rav/Fcgr4tm1Rav Tg(Ctsk-cre)1Rda/0 (conditional) |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/23/2024 MGI 6.23 |
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